PENGARUH PEMBERIAN EKSTRAK ETANOL BUNGA CENGKEH (Syzygiumaromaticum(L.) Merr.& Perry) TERHADAP WAKTU TIDUR MENCIT JANTAN
Abstract
Telah diteliti pengaruh pemberian ekstrak etanol bunga cengkeh (Syzygium aromaticum (L.) Merr. & Perry) terhadap waktu tidur mencit jantan galur jantan Swiss Webster yang diinduksi dengan fenobarbital pada dosis 100, 200 dan 400 mg / kgbb. Hasil menunjukkan bahwa ekstrak etanol bunga cengkeh pada dosis 200 dan 400 mg / kgbb dapat mempersingkat permulaan tidur mencit yang diinduksi dengan fenobarbital, berbeda reaksi terhadap kontrol positif (p <0,05). Ekstrak etanol bunga cengkeh dosis 400mg / kgbb juga dapat memperpanjang durasi tidur pada mencit yang diinduksi dengan fenobarbital yang berbeda kontak terhadap kontrol positif (p <0,05).                                                                                                  Kata kunci: bunga cengkeh, hipnotik-sedatif, fenobarbitalÂReferences
Ulung, G., 2014, “Sehat Alami dengan Herbalâ€, PT. Gramedia Pustaka Utama, Jakarta, Hlm. 132-133.
Pewe, E., 2006,“Apotek Hidup untuk Kesehatan Manusiaâ€, CV. Citra Cipta Purwosari, Jakarta, Hlm. 22, 28-29.
Pinto, E., Vale-Silva ,L., Cavaleiro, C., and L. Salgueiro., 2009, “Antifungal activity of the clove essential oil from Syzygium aromaticum on Candida, Aspergillus and Dermatophyte Speciesâ€, Journal of Medical Microbiology, 58, 1454–1462.
Pandey, A., P. Singh., 2011 “Antibacterial activity of Syzygium aromaticum (clove) with metal ion effect against food borne pathogensâ€,Asian Journal of Plant Science and Research, 1 (2):69-80.
Priyono, P. D. A., 2010, “Uji Afrodisiaka Infusa Kuncup Bunga Cengkeh (Syzygium aromaticum (L.) Meer&Perry) terhadap Libido Tikus Jantanâ€, Tugas Akhir Sarjana Farmasi, Fakultas Farmasi, Universitas Muhammadiyah Surakarta, Surakarta.
Adli, D. E. H., Kahloula, K., Silmani, M., Lahouel, Z., A. Belmahi., 2014, “The Efficacy of Syzygium aromaticum Essential Oil in Cognitive Disorders against Manganese Chronic Exposure in Rats during Developmentâ€, Not Sci Biol, 6(2):131-137.
Dasti-R, M, H., A. Morshedi., 2009, “The effects of Syzygium aromaticum (clove) on Learning and Memory in Miceâ€, Asian Journal of Traditional Medicinis, 4 (4).
Boudou, F., Berroukche, A., Bendahmane-Salmi, M., Kandouci, B, A., Adli, D. E. H., N. Tou., 3013, “Ameliorative Effects of Syzygium aromaticum Essential Oil on Fertility in Male Rats Exposed to Manganeseâ€, Advances in Sexual Medicine, 3, 85-91.
Puradisastra, S., Rosnaeni, dan I. Budiman., 2010, “Efek Hipnotik Biji Seledri (Apium Grafeolens L.) pada Mencit Jantan Galur Ddy dan Pengaruhnya Terhadap waktu Reaksi Sederhana (WRS) pada Manusiaâ€, Jurnal, Fakultas Kedokteran, Universitas Kristen Maranatha, Bandung. Hlm. 60.
Rahadian, D. D., 2009, “Pengaruh Ekstrak Biji Pala (MyristicafragnansHoutt) Dosis 7,5mg/25mgBB Terhadap Waktu Indeks Tidur dan Lama Waktu Tidur Mencit Balb/C yang Diinduksi Thiopentalâ€, Laporan Akhir Karya Tulis Ilmiah, Fakultas Kedokteran-Universitas Diponegoro, Semarang. Hlm. 12.
Erasmo, A.P.,2014,“Insomniaâ€,http://www.medicinet.com/artikel/1187,Diakses21 september 2015.
Suyono, S., 2001, “Buku Ajar Ilmu Penyakit Dalamâ€, Edisi III, Jilid 2, FKUI, Jakarta, Hlm. 778.
Nuzband, K. N., 2014, “Uji Aktivitas Antidepresan Ekstrak Bunga Cengkeh (Syzygium aromaticum) Pada Mencit Putih (Mus Musculus) Jantan Dengan Metode Forced Swim Testâ€, Karya Tulis Ilmiah, Akademi Farmasi Samarinda, Samarinda, Hlm. 2, 7-8.
Pewe, E., 2006,“Apotek Hidup untuk Kesehatan Manusiaâ€, CV. Citra Cipta Purwosari, Jakarta, Hlm. 22, 28-29.
Pinto, E., Vale-Silva ,L., Cavaleiro, C., and L. Salgueiro., 2009, “Antifungal activity of the clove essential oil from Syzygium aromaticum on Candida, Aspergillus and Dermatophyte Speciesâ€, Journal of Medical Microbiology, 58, 1454–1462.
Pandey, A., P. Singh., 2011 “Antibacterial activity of Syzygium aromaticum (clove) with metal ion effect against food borne pathogensâ€,Asian Journal of Plant Science and Research, 1 (2):69-80.
Priyono, P. D. A., 2010, “Uji Afrodisiaka Infusa Kuncup Bunga Cengkeh (Syzygium aromaticum (L.) Meer&Perry) terhadap Libido Tikus Jantanâ€, Tugas Akhir Sarjana Farmasi, Fakultas Farmasi, Universitas Muhammadiyah Surakarta, Surakarta.
Adli, D. E. H., Kahloula, K., Silmani, M., Lahouel, Z., A. Belmahi., 2014, “The Efficacy of Syzygium aromaticum Essential Oil in Cognitive Disorders against Manganese Chronic Exposure in Rats during Developmentâ€, Not Sci Biol, 6(2):131-137.
Dasti-R, M, H., A. Morshedi., 2009, “The effects of Syzygium aromaticum (clove) on Learning and Memory in Miceâ€, Asian Journal of Traditional Medicinis, 4 (4).
Boudou, F., Berroukche, A., Bendahmane-Salmi, M., Kandouci, B, A., Adli, D. E. H., N. Tou., 3013, “Ameliorative Effects of Syzygium aromaticum Essential Oil on Fertility in Male Rats Exposed to Manganeseâ€, Advances in Sexual Medicine, 3, 85-91.
Puradisastra, S., Rosnaeni, dan I. Budiman., 2010, “Efek Hipnotik Biji Seledri (Apium Grafeolens L.) pada Mencit Jantan Galur Ddy dan Pengaruhnya Terhadap waktu Reaksi Sederhana (WRS) pada Manusiaâ€, Jurnal, Fakultas Kedokteran, Universitas Kristen Maranatha, Bandung. Hlm. 60.
Rahadian, D. D., 2009, “Pengaruh Ekstrak Biji Pala (MyristicafragnansHoutt) Dosis 7,5mg/25mgBB Terhadap Waktu Indeks Tidur dan Lama Waktu Tidur Mencit Balb/C yang Diinduksi Thiopentalâ€, Laporan Akhir Karya Tulis Ilmiah, Fakultas Kedokteran-Universitas Diponegoro, Semarang. Hlm. 12.
Erasmo, A.P.,2014,“Insomniaâ€,http://www.medicinet.com/artikel/1187,Diakses21 september 2015.
Suyono, S., 2001, “Buku Ajar Ilmu Penyakit Dalamâ€, Edisi III, Jilid 2, FKUI, Jakarta, Hlm. 778.
Nuzband, K. N., 2014, “Uji Aktivitas Antidepresan Ekstrak Bunga Cengkeh (Syzygium aromaticum) Pada Mencit Putih (Mus Musculus) Jantan Dengan Metode Forced Swim Testâ€, Karya Tulis Ilmiah, Akademi Farmasi Samarinda, Samarinda, Hlm. 2, 7-8.
Published
2018-12-10
How to Cite
JALURI, Poppy Dwi Citra; NGAZIZAH, Febri Nur.
PENGARUH PEMBERIAN EKSTRAK ETANOL BUNGA CENGKEH (Syzygiumaromaticum(L.) Merr.& Perry) TERHADAP WAKTU TIDUR MENCIT JANTAN.
Jurnal Kesehatan Borneo Cendekia, [S.l.], v. 2, n. 2, p. 206-211, dec. 2018.
ISSN 2549-1822.
Available at: <http://journal.stikesborneocendekiamedika.ac.id/index.php/jbc/article/view/125>. Date accessed: 05 oct. 2024.
Issue
Section
Articles
Keywords
Kata kunci : bunga cengkeh, hipnotik-sedatif, fenobarbital
License
Authors who publish with this journal agree to the following terms:
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).
Â
Â